INTRODUCTION
NAD+ (Nicotinamide Adenine Dinucleotide)
is a naturally occurring molecule found in virtually every cell of the body. It plays a central role in cellular energy production, metabolism, DNA repair, and normal cell function.
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| Directions | IV infusion (250–500 mL saline); SC 2–3×/week; or nasal spray once daily. |
|---|---|
| Key Benefits | Supports cellular energy production and metabolism |
OVERVIEW
NAD+ acts as a coenzyme in cellular reactions that help convert nutrients into ATP, the primary energy source used by cells. It also participates in enzymes involved in DNA repair, cellular signaling, and stress responses. NAD+ levels can change with age, metabolic stress, and other physiological factors, which has led to significant interest in NAD+ research.
AREAS OF INTERESTNAD+ has been investigated for potential roles in:
Research suggests that maintaining adequate NAD+availability may support normal mitochondrial activity, energy metabolism, and cellular maintenance. NAD+ precursors such as nicotinamide riboside (NR) and NMN are also being studied because the body can use them to increase NAD+ availability. However, claims that NAD+ supplementation or infusions can broadly reverse aging, dramatically increase energy, or prevent disease have not been firmly established by clinical evidence.
The safety and effectiveness depend heavily on the form, dose, and route of administration. Oral NAD+ precursors have been studied more extensively than direct NAD+ administration. IV NAD+ is offered by some clinics, but evidence for major health or anti-aging benefits remains limited.
NAD+ is an essential cellular coenzyme involved in energy production, metabolism, DNA repair, and cellular maintenance. Because NAD+ biology is closely connected to aging and mitochondrial function, it has become an important area of research into metabolic health, longevity, and cellular function.
